Dan Beever, 39, from Sheffield, said the drug was “essential” for those, like him, who have cystic fibrosis.
“My pancreas doesn’t work as it should, so Creon is a replacement for enzymes which help absorb nutrients that I don’t generate naturally,” he said.
Mr Beever said living with the disease was a “daily challenge” and he took 25-30 Creon tablets each day.
His monthly prescription of six containers of the pills had been reduced to four because of the shortages, he said.
